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CARE
Network Publications
2011
Use of beclomethasone dipropionate as rescue
treatment for children with mild persistent asthma (TREXA): a
randomised, double-blind, placebo-controlled trial.
Fernando Martinez, M.D., Vernon M. Chinchilli, Ph.D., Wayne J.
Morgan, M.D., Susan J. Boehmer, M.A., Robert F. Lemanske Jr, M.D.,
David T. Mauger, Ph.D., Robert C. Strunk, M.D Stanley J. Szefler,
M.D., Robert S. Zeiger, M.D., Ph.D., Leonard B. Bacharier, M.D.,
Elizabeth Bade, M.D., Ronina A. Covar, M.D., Noah J. Friedman, M.D.,
Theresa W. Guilbert, M.D., Hengameh Heidarian-Raissy, Pharm.D., H.
William Kelly, Pharm.D., Jonathan Malka-Rais, M.D., Michael H.
Mellon, M.D., Christine A. Sorkness, Pharm.D., Lynn
Taussig, M.D. for the Childhood Asthma Research and Education (CARE)
Network of the National Heart, Lung, and Blood Institute.
The LANCET, Vol. 377, Issue 9766, Pages
650-657.
Cost-Effectiveness Analysis of Fluticasone vs. Montelukast in
Children with Mild-moderate Persistent Asthma in the Pediatric
Asthma Controller Trial.
Li Wang, Chris Hollenbeak, Dave Mauger, Chris Sorkness, Robert
Zeiger, Ian Paul, Rob Lemanske, Fernando Martinez, Robert Strunk,
Stan Szefler, Lynn Taussig
for the Childhood Asthma Research and Education (CARE) Network of
the National Heart, Lung, and Blood Institute.
The Journal of Allergy and
Clinical Immunology, Vol. 127, Issue 1, Pages 161-166.e1.
2010
Urinary Leukotriene E4/Exhaled Nitric
Oxide Ratio and Montelukast Response in Childhood Asthma.
Nathan Rabinovitch, MD, Nora J Graber, MS, Vernon M.
Chinchilli, PhD, Christine A. Sorkness, PharmD, Robert S. Zeiger MD,
PhD, Robert C Strunk, MD, Leonard B. Bacharier, Fernando D.
Martinez, MD,
Stanley J. Szefler, MD. for the Childhood Asthma Research and
Education (CARE) Network of the National Heart, Lung, and Blood
Institute.
The Journal of Allergy and Clinical Immunology, Vol. 126, Issue 3,
Pages 545-551,e4.7/8/10.
Forced expiratory flow between 25% and 75% of vital capacity and FEV1/forced
vital capacity ratio in relation to Clinical and physiologic
parameters in asthmatic children with normal FEV1 Values.
Michael R Simon, MD, Vernon
Chinchilli, PhD, Brenda R. Phillips, MS, Chris Sorkness, PharmD,
Robert Lemanske, Jr., MD, Stanley J. Szefler, MD, Lynn Taussig, MD,
Leonard Bacharier, MD, Wayne Morgan, MD, for the Childhood Asthma
Research and Education (CARE) Network of the National Heart, Lung,
and Blood Institute.
The Journal of Allergy and
Clinical Immunology.
Vol. 126, issue 3,
pages 527-534.e8.
Step-up Therapy for Children with
Uncontrolled Asthma while Receiving Inhaled Corticosteroids.
Robert F. Lemanske,
Jr., M.D., David T. Mauger, Ph.D., Christine A. Sorkness, Pharm.D.,
Daniel J. Jackson, M.D., Susan J. Boehmer, M.S., Fernando D.
Martinez, M.D., Robert C. Strunk, M.D., Stanley J. Szefler, M.D.,
Robert S. Zeiger, M.D., Ph.D., Leonard B. Bacharier, M.D., Ronina A.
Covar, M.D., Theresa W. Guilbert, M.D., Gary Larsen, M.D., Wayne J.
Morgan, M.D., Mark H. Moss, M.D., Joseph D. Spahn, M.D., and Lynn M.
Taussig, M.D., for the Childhood Asthma Research and Education
(CARE) Network of the National Heart, Lung, and Blood Institute.
Published Online March 2, 2010 (DOI: 10.1056/NEJMoa1001278).
Relationship Between
Infant Weight Gain and Later Asthma.
Paul IM, Camera L,
Zeiger RS, Guilbert TW, Bacharier LB, Taussig LM, Morgan WJ, Covar
RA, Krawiec M, Bloomberg GR, Mauger DT.
Pediatric Allergy and
Immunology 2010: 21: 82-89.
2009
Phenotypic predictors of long-term response to inhaled corticosteroid and leukotriene modifier therapies in pediatric asthma.
J. Knuffman, C. Sorkness, R. Lemanske Jr., D. Mauger, S. Boehmer, F. Martinez, L. Bacharier, R. Strunk, S. Szefler, R. Zeiger
Taussig, L. and the Childhood Asthma Research and Education Network of the National Heart, Lung, and Blood Institute.
Journal of Allergy and Clinical Immunology.
(2009) Volume 123, Issue 2, Pages 411-416
Impulse oscillometry versus spirometry in a long-term study of controller
therapy for pediatric asthma.
Gary L. Larsen, Wayne Morgan, Gregory P. Heldt, David T. Mauger, Susan J. Boehmer, Vernon M. Chinchilli, Robert F. Lemanske Jr.,
Fernando Martinez, Robert C. Strunk, Stanley J. Szefler, Robert S. Zeiger, Lynn M. Taussig, Leonard B. Bacharier,
Theresa W. Guilbert, Shelley Radford, Christine A. Sorkness and
Childhood Asthma Research and Education Network of the National
Heart Lung, and Blood Institute.
Journal of Allergy and Clinical Immunology, April 2009,
Volume 123, Issue 4, pgs. 861-867.
Patient characteristics
associated with improved outcomes with use of an inhaled
corticosteroid in preschool children at risk for asthma.
Leonard B. Bacharier,
Theresa W. Guilbert, Robert S. Zeiger, Robert C. Strunk, Wayne J.
Morgan, Robert F. Lemanske, Mark Moss, Stanley J. Szefler, Marzena
Krawiec, Susan Boehmer, David Mauger, Lynn M. Taussig, Fernando D.
Martinez, Childhood Asthma Research and Education Network of the
National Heart, Lung, and Blood Institute.
The Journal of Allergy and Clinical Immunology, May
2009, Volume 123, issue 5, pgs.1077-1082.e5.
Signs and Symptoms that Precede Wheezing in
Children with Moderate to Severe Intermittent Wheezing.
Kathy Rivera-Spoljaric,
Vernon M. Chinchilli, Lindsay J. Camera, Robert S. Zeiger, Ian
M. Paul, Brenda R. Phillips, Lynn M. Taussig, Robert C. Strunk,
Leonard B. Bacharier, Childhood Asthma Research and Education
(CARE) Network.
The Journal of Pediatrics, June,
2009, Volume 154, Issue 6, pages 877-881.e4.
Elevated Exhaled Nitric oxide Levels Increasae Risk of Respiratory
Tract Illness in Preschool Children with Moderate to Severe
Intermittent Wheezing.
A.
Beigelman, L. Bacharier, D. Mauger, B. Phillips, R. Zeiger, L.
Taussig, R. Strunk. Annals of Allergy, Asthma, & Immunology,
Vol. 103, No. 2, August 2009, pp.108-113.
2008
Episodic use of an inhaled corticosteroid or leukotriene
receptor antagonist in preschool children with
moderate-to-severe intermittent wheezing.
Bacharier LB, Phillips BR, Zeiger RS, Szefler SJ, Martinez FD, Lemanske RF Jr, Sorkness CA,
Bloomberg GR, Morgan WJ, Paul IM, Guilbert T, Krawiec M, Covar R, Larsen G, Mellon M, Moss MH,
Chinchilli VM, Taussig LM, Strunk RC; CARE Network.
J Allergy Clin Immunol.
(2008) Dec;122:6:1127-1135.e8
Factors associated with asthma exacerbations
during a long-term clinical trial of controller medications in
children.
Ronina A. Covar, MD,a Stanley J. Szefler, MD,a Robert S. Zeiger, MD, PhD,b Christine A. Sorkness, PharmD,c Mark Moss,
MD,c David T. Mauger, PhD,d Susan J. Boehmer, PhD,d Robert C. Strunk, MD,e Fernando D. Martinez, MD,f
and Lynn M. Taussig, MD,a for the Childhood Asthma Research and Education Network Denver, Colo, San Diego, Calif,
Madison, Wis, Tucson, Ariz, St Louis, Mo, and Hershey, Pa.
American Academy of Allergy, Asthma & Immunology (2008); 122:4:741-747.e4
Azithromycin or montelukast as inhaled corticosteroid–sparing agents in moderate-to-
severe childhood asthma study.
Robert C. Strunk, MD, Leonard B. Bacharier, MD,
Brenda R. Phillips, MS, Stanley J. Szefler, MD,Robert S. Zeiger, MD, PhD,
Vernon M. Chinchilli, PhD, Fernando D. Martinez, MD, Robert F. Lemanske, Jr, MD,
Lynn M. Taussig, MD, David T. Mauger, PhD, Wayne J. Morgan, MD, Christine A. Sorkness, PharmD,
Ian M. Paul, MD, Theresa Guilbert, MD, Marzena Krawiec, MD, Ronina Covar, MD, Gary Larsen, MD,
and the Childhood Asthma Research and Education Network of the National Heart, Lung, and Blood Institute.
American Academy of Allergy, Asthma & Immunology (2008);
122:6:1138-1144.e4
2007
Severe intermittent wheezing in preschool children: A distinct
phenotype.
Bacharier LB, Phillips BR, Bloomberg GR,
Zeiger RS, Paul IM, Krawiec M, Guilbert T, Chinchilli VM, Strunk RC,
for the Childhood Asthma Research and Education Network of the
National Heart, Lung, and Blood Institute.
Journal of
Allergy and Clinical Immunology (2007); 119: 604-610.
Long-term comparison of 3 controller regimens for
mild-moderate persistent childhood asthma: The Pediatric Asthma
Controller Trial.
Christine A. Sorkness, PharmD, Robert F. Lemanske,
Jr, MD, David T. Mauger, PhD, Susan J. Boehmer, MA, Vernon M.
Chinchilli, PhD, Fernando D. Martinez, MD, Robert C. Strunk, MD,
Stanley J. Szefler, MD, Robert S. Zeiger, MD, PhD, Leonard B.
Bacharier, MD, Gordon R. Bloomberg, MD, Ronina A. Covar, MD, Theresa
W. Guilbert, MD, Gregory Heldt, MD, Gary Larsen, MD, Michael H.
Mellon, MD, Wayne J. Morgan, MD, Mark H. Moss, MD, Joseph D. Spahn,
MD, and Lynn M. Taussig, MD.
J Allergy Clin Immunol (2007);119:64-72.
2006
Response profiles to fluticasone and montelukast in
mild-to-moderate persistent childhood asthma.
Zeiger RS,
Szefler SJ, Phillips BR, Schatz M, Martinez FD, Chinchilli VM,
Lemanske RF, Strunk RC, Larsen G, Spahn JD, Bacharier LB,
Bloomberg GR, Guilbert TW, Heldt G, Morgan WJ, Moss MH,
Sorkness CA, Taussig LM.
J
Allergy Clin Immunol (2006); 117:1:45-52.
Long-Term Inhaled Corticosteroids in Preschool Children at High Risk
for Asthma.
Theresa
W. Guilbert, M.D., Wayne J. Morgan, M.D., Robert S. Zeiger, M.D.,
Ph.D., David T. Mauger, Ph.D., Susan J. Boehmer, M.A., Stanley J.
Szefler, M.D., Ph.D., Leonard B. Bacharier, M.D., Robert F. Lemanske,
Jr., M.D., Robert C. Strunk, M.D., David B. Allen, M.D., Gordon R.
Bloomberg, M.D., Gregory Heldt, M.D., Marzena Krawiec, M.D., Gary
Larsen, M.D., Andrew H. Liu, M.D., Vernon M. Chinchilli, Ph.D.,
Christine A. Sorkness, Pharm.D., Lynn M. Taussig, M.D., and Fernando
D. Martinez, M.D.
N Engl J Med (2006);
354:19:1985-1997.
2005
Characterization of Within-Subject
Responses to Fluticasone and
Montelukast in Childhood Asthma.
Szefler SJ,
Phillips B, Martinez FD, Chinchilli VM, Lemanske RF, Strunk RC,
Zeiger RS, Larsen G, Spahn JD, Bacharier LB, Bloomberg GR, Guilbert
TW, Heldt G, Morgan WJ, Moss MH, Sorkness CA, Taussig LM. J Allergy
Clin Immunol (2005); 115:233-242.
Web-based distributed data management in the Childhood Asthma
Research and Education (CARE) Network.
Schmidt
JR, Vignati AJ, Pogash RM, Simmons VA, Evans RL. Clinical Trials
(2005); 2:50-60
A General Class of Correlation Coefficients
for the 2 X 2 Crossover Design.
Chinchilli
VM, Phillips BR, Mauger DT, Szefler, SJ.
Biometrical Journal (2005); 47:5:644-653.
2004
The Prevention of Early Asthma in Kids study: design, rationale
and methods for the Childhood Asthma Research and Education network.
Guilbert TW, Morgan WJ, Krawiec M, Lemanske RF Jr, Sorkness C, Szefler SJ,
Larsen G, Spahn JD, Zeiger RS, Heldt G, Strunk RC, Bacharier LB,
Bloomberg GR, Chinchilli VM, Boehmer SJ, Mauger EA, Mauger DT,
Taussig LM, Martinez FD.
Control Clin Trials. (2004); 25:286-310.
Classifying Asthma Severity in Children-Mismatch Between Symptoms,
Medication Use and Lung Function.
Bacharier
LB, Strunk RC, Mauger D, White D, Lemanske RF, Sorkness CA.
Am J Repir Crit Care Med.
(2004); 170:426-432.
Atopic Characteristics of Children with
Recurrent Wheezing at high risk for the development of childhood
asthma.
Guilbert
TW, Morgan WJ, Zeiger RS, Bacharier L, Boehmer SJ, Krawiec M, Larsen
G, Lemanske RF, Liu A, Mauger DT, Sorkness C, Szefler SJ, Strunk RC,
Taussig L, Martinez F.
J Allergy Clin Immunol (2004); 114:1282-1287.
2003
Relationship of exhaled nitric oxide to clinical and inflammatory
markers of persistent asthma in children.
Strunk RC,
Szefler SJ, Phillips BR, Zeiger RS, Chinchilli VM, Larsen G, Hodgdon
K, Morgan W, Sorkness CA, Lemanske RF Jr.
J. Allergy
Clin Immunol (2003); 112:883-892.
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